2026-10-19 01:08:00 - Anam and Silvia present their work at ANA
Anam and Silvia presented their work at the 2026 American Neurological Association conference. They are rigorously characterizing the postictal state in a preclinical Dravet model, thereby establishing an experimental platform for the identification of treatments that reduce postictal severity and duration. We are excited to share their exciting work, which they will also present this work at AES and SfN this fall. Congratulations, Anam and Silvia!
2026-10-01 15:02:09 - Meiling’s work is online as a bioRxiv pre-printMeiling's first author work is now on
bioRxiv! This manuscript investigates the impact of seizures on noradrenergic circuitry, crucial to understanding the impairment of consciousness during and after seizures. Meiling and her team found that seizures acutely inhibit cell bodies within the locus coeruleus, but paradoxically trigger a supraphysiologic release of norepinephrine downstream. We furthermore demonstrated that local activity within downstream regions could trigger release of norepinephrine, independent of somatic activation in the locus coeruleus, partially mediated by local glutamate receptor binding. Thank you to all of the co-authors, including Drs.
Yulong Li,
Paul Kramer,
Christian Burgess, and
Sam McKenzie, for their valuable contributions to this work.
2026-09-24 23:38:44 - Game night
It's not all work, all the time... Mattis lab members self-assembled for a Thursday night game night.
2026-09-09 23:43:07 - Kicking off the 2026-2027 academic year
Joanna presented a "State of the lab" address for our first lab meeting of the academic year. It was exciting to reunite with our lab's many returning undergraduate students, and to welcome two new students, Sasha and Jasmine, to the team. Lots of exciting milestones are anticipated soon, including multiple manuscript planned for submission by the end of 2026.
2026-08-31 12:31:44 - Welcoming new students to the Mattis lab
We are happy to welcome several new undergraduate students to the Mattis lab for the 2026-2027 academic year. Sasha Ghai, a sophomore BCN major, will join the team characterizing the postictal phenotype in the Dravet model. Jasmine Ogutu, a sophomore Neuroscience major, will investigate a novel gene therapy approach to extend survival in an Scn8a model. Welcome to the team!
