The role of subcortical neuromodulatory networks in seizures

While cortical and limbic regions are known to be highly susceptible to seizures, converging evidence suggests that subcortical neuromodulatory networks may regulate when and how seizures start and propagate.

The impact of chronic epilepsy on neuromodulatory networks

Although epilepsy is defined by recurrent seizures, its comorbid disorders – of attention, sleep mood, and cognition – are highly prevalent and often devastating to patients.