Dec 12, 2023 - First seizures recorded under the 2P with both EEG & imaging!
After months of hard work, Meiling successfully recorded seizures under the 2P! She is now able to collect simultaneous EEG and imaging data while evoking seizures with hyperthermia, which will yield lots of interesting data! Way to go, Meiling!
After months of hard work, Meiling successfully recorded seizures under the 2P! She is now able to collect simultaneous EEG and imaging data while evoking seizures with hyperthermia, which will yield lots of interesting data! Way to go, Meiling!
Nov 30, 2023 - Meiling is awarded a DSF postdoctoral fellowship!
Meiling was selected for a postdoctoral fellowship award from the Dravet Syndrome Foundation! The DSF supports and funds research on Dravet syndrome with the aims of finding new treatments and improving the quality of life for people living with Dravet Syndrome. Thank you, DSF, and congratulations, Meiling!
Meiling was selected for a postdoctoral fellowship award from the Dravet Syndrome Foundation! The DSF supports and funds research on Dravet syndrome with the aims of finding new treatments and improving the quality of life for people living with Dravet Syndrome. Thank you, DSF, and congratulations, Meiling!
Nov 28, 2023 - Nagham presents at an undergraduate poster session
Nagham gives a poster presentation of her project to cap off her independent study research course. Congratulations, Nagham!
Nagham gives a poster presentation of her project to cap off her independent study research course. Congratulations, Nagham!
Oct 20, 2023 - Krystal gives a Department of Pharmacology seminar
Krystal presents her work to the Department of Pharmacology. The talk was very well attended and the audience asked many great questions. Well done, Krystal!
Krystal presents her work to the Department of Pharmacology. The talk was very well attended and the audience asked many great questions. Well done, Krystal!
Oct 19, 2023 - Joanna gives an NETP seminar
Joanna gives a seminar for the Neural Engineering Training Program. Thanks for all the great questions!
Joanna gives a seminar for the Neural Engineering Training Program. Thanks for all the great questions!
Oct 16, 2023 - Joanna presents at PCEM
Joanna gives an invited talk at the Park City Epilepsy Meeting. This is a wonderful meeting focused on neuroscience as applied to therapy development for the treatment of epilepsy. Thank you to the meeting co-chairs, Karen Wilcox and Scott Baraban, for the invitation!
Joanna gives an invited talk at the Park City Epilepsy Meeting. This is a wonderful meeting focused on neuroscience as applied to therapy development for the treatment of epilepsy. Thank you to the meeting co-chairs, Karen Wilcox and Scott Baraban, for the invitation!
Oct 12, 2023 - Joanna presents at the Kresge Hearing Research Institute HBCS Seminar
Joanna gives an invited talk at the Hearing, Balance, and Chemical Senses (HBCS) Seminar Series. Thanks for the great questions and feedback!
Joanna gives an invited talk at the Hearing, Balance, and Chemical Senses (HBCS) Seminar Series. Thanks for the great questions and feedback!
Oct 12, 2023 - Anam joins the lab
We are pleased to welcome Anam Noor to the Mattis lab! She is freshman neuroscience student at the University of Michigan. She has a passion for neuroscience and aspires to become a neurologist. Welcome to the lab, Anam!
We are pleased to welcome Anam Noor to the Mattis lab! She is freshman neuroscience student at the University of Michigan. She has a passion for neuroscience and aspires to become a neurologist. Welcome to the lab, Anam!
Oct 09, 2023 - First seizure recording using Open Ephys!
Open Ephys is working, as evidenced by this beautiful seizure recording! This platform will enable our lab to set up a closed-loop system in which real-time, automated seizure detection triggers optogenetic stimulation.
Open Ephys is working, as evidenced by this beautiful seizure recording! This platform will enable our lab to set up a closed-loop system in which real-time, automated seizure detection triggers optogenetic stimulation.
Sep 13, 2023 - Kat joins the lab
We are so glad to welcome Katherine (Kat) Reaume to the lab as a research assistant! Kat is an MSU graduate with a B.S. in neuroscience and a minor in philosophy. She is working as an EEG technician at Beaumont Hospital while also completing a post-bac at MSU, all towards her future goal to become a doctor. Welcome, Kat!
We are so glad to welcome Katherine (Kat) Reaume to the lab as a research assistant! Kat is an MSU graduate with a B.S. in neuroscience and a minor in philosophy. She is working as an EEG technician at Beaumont Hospital while also completing a post-bac at MSU, all towards her future goal to become a doctor. Welcome, Kat!
Aug 28, 2023 - Izzy joins the lab
We are happy to welcome Isabella (Izzy) Plati to the Mattis lab! She joins our lab as a fourth-year neuroscience student at the University of Michigan. Her prior research experience includes investigation of phenotype inheritance in the nematode C. elegans. She is highly active in the community, including working with an organization called Medicine4Youth and leading a team of high school students to complete a research project. She aspires to become a physician-scientist specializing in pediatric epilepsy. Welcome, Izzy!
We are happy to welcome Isabella (Izzy) Plati to the Mattis lab! She joins our lab as a fourth-year neuroscience student at the University of Michigan. Her prior research experience includes investigation of phenotype inheritance in the nematode C. elegans. She is highly active in the community, including working with an organization called Medicine4Youth and leading a team of high school students to complete a research project. She aspires to become a physician-scientist specializing in pediatric epilepsy. Welcome, Izzy!
Aug 22, 2023 - Saying farewell to our summer students
Lab dinner at the Ann Arbor "1923 Taco Bus" to celebrate the end of the summer, and to say goodbye to our three wonderful summer students, Kami, Shahriar, and Jade.
Lab dinner at the Ann Arbor "1923 Taco Bus" to celebrate the end of the summer, and to say goodbye to our three wonderful summer students, Kami, Shahriar, and Jade.
Aug 16, 2023 - Rida receives a U@MNI research fellowship
Rida Qureshi was awarded a competitive U@MNI undergraduate research fellowship to support her work in the lab. Congratulations, Rida!
Rida Qureshi was awarded a competitive U@MNI undergraduate research fellowship to support her work in the lab. Congratulations, Rida!
Aug 04, 2023 - Julia heads to grad school
Julia Kravchenko, one of the lab's founding members, has "graduated" from being a technician in the lab and is starting a PhD in the Neuroscience Graduate Program at the University of Michigan! She'll be greatly missed, but we're excited for her (and glad she'll still be nearby). Best wishes, Julia!
Julia Kravchenko, one of the lab's founding members, has "graduated" from being a technician in the lab and is starting a PhD in the Neuroscience Graduate Program at the University of Michigan! She'll be greatly missed, but we're excited for her (and glad she'll still be nearby). Best wishes, Julia!
Jun 15, 2023 - The Mattis lab turns 1!
It's hard to believe that our doors opened just one year ago. So proud of the lab and team we've built, and looking forward to the year ahead!
It's hard to believe that our doors opened just one year ago. So proud of the lab and team we've built, and looking forward to the year ahead!
Jun 12, 2023 - Kamie joins the lab for summer 2023
We are very excited to welcome Kamie, a rising sophomore at Johns Hopkins, to the lab for the summer. Kamie is studying biomedical engineering and has previously worked as a research assistant in Dr. Lisa Larkin’s Skeletal Tissue Engineering Laboratory at UMich.
We are very excited to welcome Kamie, a rising sophomore at Johns Hopkins, to the lab for the summer. Kamie is studying biomedical engineering and has previously worked as a research assistant in Dr. Lisa Larkin’s Skeletal Tissue Engineering Laboratory at UMich.
Jun 12, 2023 - Shahriar joins the lab for summer 2023
We are very excited to welcome Shahriar, a rising senior at Kalamazoo College, as an undergraduate student researcher for the summer of 2023. Shahriar is majoring in Computer Science with a Neuroscience concentration and a minor in Psychology. He received an Internship Stipend Award as well as the competitive Hough Foundation Grant from Kalamazoo College in support of his summer research. Congratulations and welcome, Shahriar!
We are very excited to welcome Shahriar, a rising senior at Kalamazoo College, as an undergraduate student researcher for the summer of 2023. Shahriar is majoring in Computer Science with a Neuroscience concentration and a minor in Psychology. He received an Internship Stipend Award as well as the competitive Hough Foundation Grant from Kalamazoo College in support of his summer research. Congratulations and welcome, Shahriar!
Jun 12, 2023 - Meiling joins the lab
We are thrilled to welcome Meiling to the Mattis lab as our second postdoc! Meiling completed her PhD in the Department of Molecular, Cellular, and Developmental Biology, along with a dual master's degree in the Department of Computational Medicine and Bioinformatics, both at the University of Michigan. Working in Sam Kwon's lab, she uncovered neuronal mechanisms of impaired perceptual learning associated with neurodevelopmental disorders using a mouse model of Synaptic Ras-GTPase-activating protein (SynGAP), behavioral testing, and in vivo two-photon calcium imaging.
We are thrilled to welcome Meiling to the Mattis lab as our second postdoc! Meiling completed her PhD in the Department of Molecular, Cellular, and Developmental Biology, along with a dual master's degree in the Department of Computational Medicine and Bioinformatics, both at the University of Michigan. Working in Sam Kwon's lab, she uncovered neuronal mechanisms of impaired perceptual learning associated with neurodevelopmental disorders using a mouse model of Synaptic Ras-GTPase-activating protein (SynGAP), behavioral testing, and in vivo two-photon calcium imaging.
Jun 05, 2023 - Krystal is selected for the PSTP T32!
We are so excited to share the news that Krystal has been selected to to be appointed as a trainee on the highly competitive Pharmacological Sciences Training Program (PSTP) T32 training grant. This training program is a collaboration between the Medical School and the College of Pharmacy, designed to provide translational education, research training, and career development for trainees, to equip them as leaders in the field of experimental therapeutics. Congratulations, Krystal!!!
We are so excited to share the news that Krystal has been selected to to be appointed as a trainee on the highly competitive Pharmacological Sciences Training Program (PSTP) T32 training grant. This training program is a collaboration between the Medical School and the College of Pharmacy, designed to provide translational education, research training, and career development for trainees, to equip them as leaders in the field of experimental therapeutics. Congratulations, Krystal!!!
Jun 05, 2023 - Mattis lab receives a Research Scouts Award!
We are thrilled to be the recipients of a Scouts Award from the University of Michigan. The Research Scouts program is an investment in the "Bold Science" objective of Michigan Medicine's research strategic plan, with the goal of catalyzing new and exciting lines of investigation. Scouts Awards are intended to fund early stage ideas that challenge common dogma and have the potential to be paradigm shifting. Thank you to the Research Scout who selected our lab!
We are thrilled to be the recipients of a Scouts Award from the University of Michigan. The Research Scouts program is an investment in the "Bold Science" objective of Michigan Medicine's research strategic plan, with the goal of catalyzing new and exciting lines of investigation. Scouts Awards are intended to fund early stage ideas that challenge common dogma and have the potential to be paradigm shifting. Thank you to the Research Scout who selected our lab!
Jun 02, 2023 - Chandni is selected for the NETP T32!
Chandni has been awarded the highly competitive Neural Engineering Training Program (NETP) T32. The NETP enhances the graduate school experience of trainees with a wide variety of activities (seminars, journal clubs, an annual symposium, social events, and workshops) focused on neural engineering. Congratulations, Chandni!!!
Chandni has been awarded the highly competitive Neural Engineering Training Program (NETP) T32. The NETP enhances the graduate school experience of trainees with a wide variety of activities (seminars, journal clubs, an annual symposium, social events, and workshops) focused on neural engineering. Congratulations, Chandni!!!
May 15, 2023 - Chandni presents at the NETP Symptosium
Chandni presented her project at the annual Neural Engineering Training Program Symposium. This was our lab's first presentation of new data (collected within the Mattis lab), which is a major milestone!
Chandni presented her project at the annual Neural Engineering Training Program Symposium. This was our lab's first presentation of new data (collected within the Mattis lab), which is a major milestone!
Apr 26, 2023 - Joe is admitted to the MCDB Masters of Science program at UofM!
Very proud to announce that Joe will be pursuing an MS in the Department of Molecular, Cellular, and Developmental Biology (MCDB) beginning fall term, 2023! Fortunately for us, he'll still be able to continuing his position in the lab at the same time. Way to go, Joe!
Very proud to announce that Joe will be pursuing an MS in the Department of Molecular, Cellular, and Developmental Biology (MCDB) beginning fall term, 2023! Fortunately for us, he'll still be able to continuing his position in the lab at the same time. Way to go, Joe!
Apr 25, 2023 - Joanna presents at the American Academy of Neurology conference
Joanna gives an invited talk at the AAN Research Career Symposium in Boston.
Joanna gives an invited talk at the AAN Research Career Symposium in Boston.
Apr 14, 2023 - First fiber photometry experiment is underway!
So thrilled to be collecting fiber photometry and ECoG data during seizures! Great job Chandni, and thank you so much to Burgess lab collaborating with us on this!
So thrilled to be collecting fiber photometry and ECoG data during seizures! Great job Chandni, and thank you so much to Burgess lab collaborating with us on this!
Apr 03, 2023 - Chandni is selected as a student rep for the NGP DEI committee
Congratulations, Chandni!
Congratulations, Chandni!
Mar 24, 2023 - Chandni officially joins the lab
We are very excited to welcome Chandni Rana as a graduate student in the Mattis lab! Chandni graduated from the University of Florida with a B.S. in Biomedical Engineering and gained additional experience as a lab technician at NYU. She is a student in the Neuroscience Graduate Program (NGP) at the University of Michigan.
We are very excited to welcome Chandni Rana as a graduate student in the Mattis lab! Chandni graduated from the University of Florida with a B.S. in Biomedical Engineering and gained additional experience as a lab technician at NYU. She is a student in the Neuroscience Graduate Program (NGP) at the University of Michigan.
Mar 01, 2023 - Krystal officially joins the lab
We are thrilled to welcome Krystal M. Santiago-Colón as the lab's first official graduate student! Krystal graduated from the University of Puerto Rico, Cayey Campus with a B.S. in Biology in 2022. She is a student in the Program in Biomedical Sciences (PIBS) and the Department of Pharmacology. Krystal will be jointly mentored by Dr. Lori Isom, Chair of the Department of Pharmacology.
We are thrilled to welcome Krystal M. Santiago-Colón as the lab's first official graduate student! Krystal graduated from the University of Puerto Rico, Cayey Campus with a B.S. in Biology in 2022. She is a student in the Program in Biomedical Sciences (PIBS) and the Department of Pharmacology. Krystal will be jointly mentored by Dr. Lori Isom, Chair of the Department of Pharmacology.
Feb 28, 2023 - Setting up an automated fluorescent microscope + stereology system!
Today our new automated Nikon fluorescent microscope was installed! We'll be using this alongside a MBF Biosciences software for stereology. So excited to start taking pictures on this microscope!
Today our new automated Nikon fluorescent microscope was installed! We'll be using this alongside a MBF Biosciences software for stereology. So excited to start taking pictures on this microscope!
Feb 27, 2023 - Julia will be joining the NGP at UofM next year!
Julia accepted an offer of admission from the Neuroscience Graduate Program at the University of Michigan! She will be greatly missed, but so excited for her next step!
Julia accepted an offer of admission from the Neuroscience Graduate Program at the University of Michigan! She will be greatly missed, but so excited for her next step!
Feb 15, 2023 - Setting up the slice rig!
The Mattis Lab now has a beautiful ephys rig for slice physiology, with integrated multi-color LED illumination for optogenetics. Thank you, Scientifica, Olympus, and Molecular Devices!
The Mattis Lab now has a beautiful ephys rig for slice physiology, with integrated multi-color LED illumination for optogenetics. Thank you, Scientifica, Olympus, and Molecular Devices!
Feb 02, 2023 - First whole cell patch clamp recording!
Slice electrophysiology is happening in the Mattis lab! And in just a few weeks we'll be able to move over onto our very own rig.
Slice electrophysiology is happening in the Mattis lab! And in just a few weeks we'll be able to move over onto our very own rig.
Feb 01, 2023 - Limei joins the lab
We are very excited to welcome Limei to the Mattis lab as our first postdoc! Limei previously completed a postdoc in Dr. Bing Ye's lab at the University of Michigan, where she investigated the mechanism of the high temporal resolution of sensory neurons in drosophila larvae.
We are very excited to welcome Limei to the Mattis lab as our first postdoc! Limei previously completed a postdoc in Dr. Bing Ye's lab at the University of Michigan, where she investigated the mechanism of the high temporal resolution of sensory neurons in drosophila larvae.
Jan 30, 2023 - First EEG recording!
We hooked up our first mice today and were so excited to see that we are able to record lovely EEG signal!
We hooked up our first mice today and were so excited to see that we are able to record lovely EEG signal!
Jan 30, 2023 - Chandni rotates in the lab
We are very happy to welcome graduate student Chandni Rana (NGP) to the lab for a rotation.
We are very happy to welcome graduate student Chandni Rana (NGP) to the lab for a rotation.
Jan 04, 2023 - First graduate students rotating in the lab
We are very happy to welcome graduate students Krystal Santiago-Colón (pharmacology) and Jacob Reeves (NGP) to the lab this winter.
We are very happy to welcome graduate students Krystal Santiago-Colón (pharmacology) and Jacob Reeves (NGP) to the lab this winter.
Dec 24, 2022 - First paper accepted: “Optogenetic and chemogenetic manipulation of seizure threshold in mice”
We were thrilled to learn that the Mattis lab's first paper has been accepted for publication in STAR Protocols! In this paper, we detail a protocol for the use of optogenetics or chemogenetics to assess the neuronal circuits contributing to seizure initiation, with a focus on hyperthermia-induced seizures. Congratulations to first author Julia Kravchenko!
We were thrilled to learn that the Mattis lab's first paper has been accepted for publication in STAR Protocols! In this paper, we detail a protocol for the use of optogenetics or chemogenetics to assess the neuronal circuits contributing to seizure initiation, with a focus on hyperthermia-induced seizures. Congratulations to first author Julia Kravchenko!
Dec 22, 2022 - Yiannos joins the lab
We are very happy to welcome Yiannos Demetriou as a new undergraduate student in the Mattis lab, starting January 2023! Yiannos is a triple major at the University of Michigan. He has multiple research experiences, ranging from designing and developing a virtual reality application, to writing and testing commands for a spider robot, to using Machine Learning to identify tinnitus in guinea pigs.
We are very happy to welcome Yiannos Demetriou as a new undergraduate student in the Mattis lab, starting January 2023! Yiannos is a triple major at the University of Michigan. He has multiple research experiences, ranging from designing and developing a virtual reality application, to writing and testing commands for a spider robot, to using Machine Learning to identify tinnitus in guinea pigs.
Dec 13, 2022 - Setting up the 2-photon!
The Mattis Lab now has a 2-photon microscope! Thank you, Bruker! We look forward to slice and in vivo imaging, coupled with optogenetic stimulation.
The Mattis Lab now has a 2-photon microscope! Thank you, Bruker! We look forward to slice and in vivo imaging, coupled with optogenetic stimulation.
Dec 01, 2022 - Joanna presents at the DSF Research Roundtable
Joanna gives an invited talk at the Dravet Syndrome Foundation Research Roundtable, held just prior to the American Epilepsy Society Annual Meeting in Nashville, Tennessee.
Joanna gives an invited talk at the Dravet Syndrome Foundation Research Roundtable, held just prior to the American Epilepsy Society Annual Meeting in Nashville, Tennessee.
Nov 09, 2022 - Juan joins the lab
We are happy to welcome Juan Disla as a new undergraduate student in the Mattis lab! He will be officially joining winter 2023 but has been getting a head start this fall. Welcome, Juan!
We are happy to welcome Juan Disla as a new undergraduate student in the Mattis lab! He will be officially joining winter 2023 but has been getting a head start this fall. Welcome, Juan!
Oct 25, 2022 - First surgery!
First stereotaxic viral injections complete in the Mattis Lab! Thousands more to go...
First stereotaxic viral injections complete in the Mattis Lab! Thousands more to go...
Sep 29, 2022 - First seizure!
Today we successfully elicited a seizure in a mouse in the Mattis Lab! The first of many...
Today we successfully elicited a seizure in a mouse in the Mattis Lab! The first of many...
Aug 25, 2022 - Nagham and Rida join the lab
We are excited to welcome to the lab our first two University of Michigan undergraduate students. Welcome, Nagham Eldroubi and Rida Qureshi!
We are excited to welcome to the lab our first two University of Michigan undergraduate students. Welcome, Nagham Eldroubi and Rida Qureshi!
Aug 04, 2022 - Joanna presents at the Epilepsy GRC
Joanna presents her post-doctoral work at the Epilepsy Gordon Research Conference, held in Barcelona, Spain.
Joanna presents her post-doctoral work at the Epilepsy Gordon Research Conference, held in Barcelona, Spain.
Jul 20, 2022 - Joanna presents at Grand Rounds
Joanna gives a talk to the Department of Neurology at the University of Michigan. Thanks to all those who attended in person or on zoom!
Joanna gives a talk to the Department of Neurology at the University of Michigan. Thanks to all those who attended in person or on zoom!
Jun 24, 2022 - Julia joins the lab
Julia Kravchenko signs on to join the lab as a Lab Technician Senior. Julia graduated from University of Michigan in 2022, with a multiple award-winning Honors Thesis entitled "Contributions of GABAergic cells in the anterior and posterior ventral pallidum on 'liking' and 'wanting'". Welcome, Julia!
Julia Kravchenko signs on to join the lab as a Lab Technician Senior. Julia graduated from University of Michigan in 2022, with a multiple award-winning Honors Thesis entitled "Contributions of GABAergic cells in the anterior and posterior ventral pallidum on 'liking' and 'wanting'". Welcome, Julia!
Jun 15, 2022 - Opening day
The official first day of the Mattis lab.
The official first day of the Mattis lab.
Jun 01, 2022 - Joe joins the lab
Joseph Barden joins the lab as a Research Laboratory Specialist Associate. Joe is an experienced technician and laboratory manager, as well as an avid pianist. Welcome, Joe!
Joseph Barden joins the lab as a Research Laboratory Specialist Associate. Joe is an experienced technician and laboratory manager, as well as an avid pianist. Welcome, Joe!
Mar 14, 2022 - Joanna publishes in eLife
Joanna’s post-doc paper (with mentor Dr. Ethan Goldberg at CHOP) is published! Read about “Corticohippocampal circuit dysfunction in a mouse model of Dravet Syndrome”: https://elifesciences.org/articles/69293
Joanna’s post-doc paper (with mentor Dr. Ethan Goldberg at CHOP) is published! Read about “Corticohippocampal circuit dysfunction in a mouse model of Dravet Syndrome”: https://elifesciences.org/articles/69293
